Some drugs used to prevent malaria (antimalarials) carry a risk for psoriasis patients.Certain antimalarial medications may trigger or exacerbate psoriasis. There are two antimalarials that have been definitely associated with psoriasis risks, Chloroquine (brand name Aralen), and Hydroxychloroquine sulfate (brand name Plaquenil). Quinacrine may also be responsible for some psoriasis flares. According to the National Psoriasis Foundation, antimalarial flare-up happen “usually 2 to 3 weeks after the drug is taken.”
The British National Travel Health Network and Centre says that there is no known psoriasis risk with the antimalarial medications proguanil, atovaquone/proguanil or mefloquine.
If you will be travelling to (or living in) a malaria-prone area, it’s good to know that there are more options than a plain “psoriasis or malaria” choice. The answer can be “neither.”