Skin-Cap
Information about the infamous psoriasis product, Skin-Cap, and its manufacturer.
Much has been written about Skin-Cap already. To summarize, Skin-Cap was sold from Spain as a psoriasis treatment containing zinc pyrithione (ZnP), but due to its quick effectiveness (ZnP isn’t known to be effective for psoriasis), and its side effect profile, some physicians suspected that it actually contained a potent steroid. When it was tested, by several independent labs, steroids were found. The manufacturer denied that the product contained steroids, and that denial (in light of the lab findings) is the basis of the FDA putting an import ban in place.
Canada gave the product a second chance, over two years after its initial ban, and ended up banning it a second time, due to the presence of another steroid in the product.
Several European countries also have bans of various sorts in place. Skin-Cap was actually banned first in Europe — Spain to be precise, and ironic in a way — years before it was banned by the FDA. At least four different steroids have been found in various versions of the product over the years. At first, Cheminova International (the manufacturer) simply denied the presence of steroids. After rumours started flying, they stopped responding to the question at all, even to people who had partnered with the company.
Obvious myths you might hear (or read) from promoters of Skin-Cap:
We sell the original formula.
Since so many different steroids have been detected over the years, how do they know?
It works because of the special zinc formula.
ZnP has never been shown to work any better than placebo for psoriasis, no matter how it was formulated. Some tests have shown a complete absence of ZnP in Skin-Cap. The claim is basically ad copy which is more than 5 years old.
There are no side effects.
Since they really don’t know what’s in Skin-Cap, how do they know?
There have never been any side effects reported.
This is absolute nonsense — see resources below.
There have never been any lawsuits.
Again, rubbish.
The testing was invalid.
A typical excuse, but it requires that all of the labs around the world which have tested the product be completely clueless about how to accurately test for the presence of a steroid.
A person should also be aware of what “Noble Formula” means. Noble Formula 1 (NF-1) is, basically, the closest guess as to what was in Skin-Cap, including the super-potent steroid. Some companies call this “Noble Formula Rx” to indicate its prescription-only status. NF-1, to be legally created, must be compounded by a pharmacy with a valid prescription and labeling instructions. Noble Formula 2 (NF-2) is the best guess as to what was in Skin-Cap except for the steroid. NF-2 products are available over-the-counter.
It should also be noted that the FDA has made it clear that no product which claims it contains ZnP as its only active ingredient can be sold as a treatment for psoriasis. There are also a number of “clones” out on the market with similar names and/or claims (such as Blue Cap, Zinc Cap, Skin-Zinc, etc.).
Please see Ed Anderson’s Skin-Cap FAQ for highly detailed information.
Links
Food and Drug Administration:
August 8, 1997: FDA Warns Consumers Not to Use Skin-Cap (also on MedWatch and the Natural Product Center’s web site)
August, 1997: News along the Pike
November/December 1997: “Skin-Cap” May Cause Harm; Users Should Call Doctor
December 17, 1997: Cheminova America recall notice and enforcement action
February 20, 1998: Import Alert #61-06
March 4, 1998: Warning Letter to Cheminova International for soliciting Skin-Cap customers in the U.S.A.
April 5, 1998: A Refusal Action for drug adulteration for a shipment of Skin-Cap spray coming from the Ukraine
May 8, 1998: Summary of Aug 8, 1997 Warning
August, 1997: News along the Pike
November/December 1997: “Skin-Cap” May Cause Harm; Users Should Call Doctor
December 17, 1997: Cheminova America recall notice and enforcement action
February 20, 1998: Import Alert #61-06
March 4, 1998: Warning Letter to Cheminova International for soliciting Skin-Cap customers in the U.S.A.
April 5, 1998: A Refusal Action for drug adulteration for a shipment of Skin-Cap spray coming from the Ukraine
May 8, 1998: Summary of Aug 8, 1997 Warning
Health Canada:
August 13, 1997: Warning regarding use of SKIN-CAP shampoo and spray
March 17, 2000: Warning not to use Skin-Cap Spray because it contains an undeclared corticosteroid hormone
Discontinued Product Information about Skin-Cap Shampoo
March 17, 2000: Warning not to use Skin-Cap Spray because it contains an undeclared corticosteroid hormone
Discontinued Product Information about Skin-Cap Shampoo
World Health Organization:
September 19, 1997: Information Exchange System Alert #64 (or here)
March 27, 2000: Information Exchange System Alert #97
March 27, 2000: Information Exchange System Alert #97
Dermatology Online Journal:
(11a) Editorial Comment (1997, No. 2)
(11b) Immediacy Is Both a Liability and an Asset of the Internet
(11c) Skin Cap: What Have We Learned, and When Did We Learn It?
(11d) Pustular Psoriasis and Hepatotoxicity Associated with use of Skin Cap Spray
(11e) Skin Cap Spray and Corticosteroids
(11f) Reply by Charles Crutchfield MD
(11g) Skin Cap Analysis in Spain
Advances in Psoriasis Treatment 6(1):4
Discussion Group Archives
(11b) Immediacy Is Both a Liability and an Asset of the Internet
(11c) Skin Cap: What Have We Learned, and When Did We Learn It?
(11d) Pustular Psoriasis and Hepatotoxicity Associated with use of Skin Cap Spray
(11e) Skin Cap Spray and Corticosteroids
(11f) Reply by Charles Crutchfield MD
(11g) Skin Cap Analysis in Spain
Advances in Psoriasis Treatment 6(1):4
Discussion Group Archives
National Psoriasis Foundation:
March 29, 2000: Skin-Cap Pulled from Canadian Market for Second Time
November/December 2000: FDA Investigating Blue Cap
November/December 2000: FDA Investigating Blue Cap
Legal Proceedings:
June 30, 2000: Cheminova America v. Corker — Appeal of certification of class-action suit fails
August 16, 2002: Default judgement against Catalysis vacated
August 16, 2002: Default judgement against Catalysis vacated
Other:
Biamonte Center for Clinical Nutrition
, where Skin-Cap was used to “kill parasites on the skin”
Bulletin of Venerology and Dermatology, 1996, No. 4
Bulletin of Venerology and Dermatology, 1997, No. 1
(Undated) Clinical Trial on the Efficacy of SKIN-CAP in Vulgar Psoriasis and Seborheic Dermatitis
Sandy Cormack talks a bit about Skin-Cap
DermDigest
August 13, 1997: Discovery Channel Canada
July 2002: Flake HQ
Health Care Reality Check
Injuryboard.com
has some old info
July 22/29, 1998: JAMA Letters
Frank Otters on Skin-Cap
Prurigo Nodularis Support Group Messages from May, 2002 and more here
The Psoriasis Association, Inc. of Australia
PsoriasisNet
D.P. Ray talks a little about Skin-Cap
Skin-Cap listed as a “definite psoriasis scam”
The Skin-Cap Story
(a timeline of events from the early 1980s to September of 1997, from the Skin Therapy Letter)
The Temporal Dermatohistopathologic Examination of Human Psoriatic Skin Treated with a Novel Topical Liquid Formulation Containing Clobetasol Propionate by Charles E. Crutchfield III, MD
University of California, Davis
University Compounding Pharmacy
Try Dose of Caution When Shopping Online
from USA Today
VOY Forum Messages
Warnings on Alternative and So-Called Natural Remedies
Bulletin of Venerology and Dermatology, 1996, No. 4
Bulletin of Venerology and Dermatology, 1997, No. 1
(Undated) Clinical Trial on the Efficacy of SKIN-CAP in Vulgar Psoriasis and Seborheic Dermatitis
Sandy Cormack talks a bit about Skin-Cap
DermDigest
August 13, 1997: Discovery Channel Canada
July 2002: Flake HQ
Health Care Reality Check
Injuryboard.com
July 22/29, 1998: JAMA Letters
Frank Otters on Skin-Cap
Prurigo Nodularis Support Group Messages from May, 2002 and more here
The Psoriasis Association, Inc. of Australia
PsoriasisNet
D.P. Ray talks a little about Skin-Cap
Skin-Cap listed as a “definite psoriasis scam”
The Skin-Cap Story
The Temporal Dermatohistopathologic Examination of Human Psoriatic Skin Treated with a Novel Topical Liquid Formulation Containing Clobetasol Propionate by Charles E. Crutchfield III, MD
University of California, Davis
University Compounding Pharmacy
Try Dose of Caution When Shopping Online
VOY Forum Messages
Warnings on Alternative and So-Called Natural Remedies
Foreign Language:
Sales
A Cream Solutions, Inc.
Advanced Alternatives Center
Beautyworks.com
Clearskin.biz
European Solutions
Life Remedy
Masters Marketing
Med Marketing, LLC
Net Nova Pharmaceuticals
NuWellness
Pharmakwik
Phdhealth.com
Psoriasis-Solution.net
SkinCap.biz
Skincap.ca
Skincappsoriasis.co.uk
(sister site to beautyworks.com)
Unique Image
VNF Nutrition
Advanced Alternatives Center
Beautyworks.com
Clearskin.biz
European Solutions
Life Remedy
Masters Marketing
Med Marketing, LLC
Net Nova Pharmaceuticals
NuWellness
Pharmakwik
Phdhealth.com
Psoriasis-Solution.net
SkinCap.biz
Skincap.ca
Skincappsoriasis.co.uk
Unique Image
VNF Nutrition
Clones: